Raman spectroscopic study on the conformation of 11 S form acetylcholinesterase from Torpedo californica

Dimitrina Aslanian; Pál Gróf; Michel Négrerie; Minko Balkanski; Palmer Taylor

doi:10.1016/0014-5793(87)81216-4

Raman spectroscopic study on the conformation of 11 S form acetylcholinesterase from Torpedo californica

Dimitrina Aslanian
, Pál Gróf
, Michel Négrerie
, Minko Balkanski
, Palmer Taylor

Sorbonne Université
Department of Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

Vibrational Raman spectroscopy has been used to study the conformation of the 11 S form of acetylcholine-sterase from Torpedo californica. Secondary structure analysis by the method of Williams [(1983) J. Mol. Biol. 166, 581-603] shows 49% α-helical structure, 23% β-sheets, 11% turns and 15% undefined structure. Secondary structure estimates obtained for this enzyme by Raman spectroscopy and circular dichroism have been analyzed.

Original language	English
Pages (from-to)	202-206
Number of pages	5
Journal	FEBS Letters
Volume	219
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(87)81216-4
Publication status	Published - 13 Jul 1987

Keywords

Acetylcholinesterase
Raman spectroscopy
Secondary structure

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10.1016/0014-5793(87)81216-4

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title = "Raman spectroscopic study on the conformation of 11 S form acetylcholinesterase from Torpedo californica",

abstract = "Vibrational Raman spectroscopy has been used to study the conformation of the 11 S form of acetylcholine-sterase from Torpedo californica. Secondary structure analysis by the method of Williams [(1983) J. Mol. Biol. 166, 581-603] shows 49\% α-helical structure, 23\% β-sheets, 11\% turns and 15\% undefined structure. Secondary structure estimates obtained for this enzyme by Raman spectroscopy and circular dichroism have been analyzed.",

keywords = "Acetylcholinesterase, Raman spectroscopy, Secondary structure",

author = "Dimitrina Aslanian and P{\'a}l Gr{\'o}f and Michel N{\'e}grerie and Minko Balkanski and Palmer Taylor",

year = "1987",

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AU - Aslanian, Dimitrina

AU - Gróf, Pál

AU - Négrerie, Michel

AU - Balkanski, Minko

AU - Taylor, Palmer

PY - 1987/7/13

Y1 - 1987/7/13

N2 - Vibrational Raman spectroscopy has been used to study the conformation of the 11 S form of acetylcholine-sterase from Torpedo californica. Secondary structure analysis by the method of Williams [(1983) J. Mol. Biol. 166, 581-603] shows 49% α-helical structure, 23% β-sheets, 11% turns and 15% undefined structure. Secondary structure estimates obtained for this enzyme by Raman spectroscopy and circular dichroism have been analyzed.

AB - Vibrational Raman spectroscopy has been used to study the conformation of the 11 S form of acetylcholine-sterase from Torpedo californica. Secondary structure analysis by the method of Williams [(1983) J. Mol. Biol. 166, 581-603] shows 49% α-helical structure, 23% β-sheets, 11% turns and 15% undefined structure. Secondary structure estimates obtained for this enzyme by Raman spectroscopy and circular dichroism have been analyzed.

KW - Acetylcholinesterase

KW - Raman spectroscopy

KW - Secondary structure

U2 - 10.1016/0014-5793(87)81216-4

DO - 10.1016/0014-5793(87)81216-4

M3 - Article

C2 - 3595873

AN - SCOPUS:0023652662

SN - 0014-5793

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EP - 206

JO - FEBS Letters

JF - FEBS Letters

IS - 1

ER -

Raman spectroscopic study on the conformation of 11 S form acetylcholinesterase from Torpedo californica

Abstract

Keywords

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