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Rebinding of Proximal Histidine in the Cytochrome c' from Alcaligenes xylosoxidans Acts as a Molecular Trap for Nitric Oxide

  • Eastern Oregon University

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Transient absorption spectra on cytochrome c’ and their kinetics were recorded to identify the formation of 5-coordinate (5c)-NO and 5c-His hemes from 4c-heme (99% and 1% amplitudes; 7-ps and 100-ps time constants, respectively). We demonstrate that proximal histidine precludes NO rebinding at the proximal site.

Original languageEnglish
Title of host publicationSpringer Series in Chemical Physics
PublisherSpringer Science and Business Media Deutschland GmbH
Pages556-558
Number of pages3
DOIs
Publication statusPublished - 1 Jan 2009

Publication series

NameSpringer Series in Chemical Physics
Volume92
ISSN (Print)0172-6218

Keywords

  • Nitric Oxide
  • Nitric Oxide
  • Singular Value Decomposition
  • Sodium Ascorbate
  • Transient Absorption Spectrum

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