Abstract
The Passerini reaction of α,β-unsaturated aldehydes with formic acid followed by a reductive Tsuji-Trost reaction affords β,γ- unsaturated amides. The overall process may be viewed as a one-carbon homologation of unsaturated aldehydes into amides.
| Original language | English |
|---|---|
| Article number | st-2014-d0326-l |
| Pages (from-to) | 1901-1903 |
| Number of pages | 3 |
| Journal | Synlett |
| Volume | 25 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - 1 Jan 2014 |
| Externally published | Yes |
Keywords
- allyl complexes
- multicomponent reaction
- palladium
- reduction
- tandem reaction