Sandmeyer trifluoromethylthiolation of arenediazonium salts with sodium thiocyanate and Ruppert–Prakash reagent

Grégory Danoun; Bilguun Bayarmagnai; Matthias F. Gruenberg; Lukas J. Goossen

doi:10.1039/c3sc53076k

Sandmeyer trifluoromethylthiolation of arenediazonium salts with sodium thiocyanate and Ruppert–Prakash reagent

Grégory Danoun
, Bilguun Bayarmagnai
, Matthias F. Gruenberg
, Lukas J. Goossen

University of Kaiserslautern

Research output: Contribution to journal › Article › peer-review

Abstract

In the presence of copper thiocyanate, sodium thiocyanate and the inexpensive, easy-to-use trifluoromethylating reagent Me₃Si–CF₃, diazonium salts are smoothly converted into the corresponding aryl trifluoromethyl thioethers. Combined with diazotisation, this convenient and inexpensive method allows the straightforward synthesis of aryl or heteroaryl trifluoromethyl thioethers from the corresponding anilines.

Original language	English
Pages (from-to)	1312-1316
Number of pages	5
Journal	Chemical Science
Volume	5
Issue number	4
DOIs	https://doi.org/10.1039/c3sc53076k
Publication status	Published - 3 Mar 2014
Externally published	Yes

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title = "Sandmeyer trifluoromethylthiolation of arenediazonium salts with sodium thiocyanate and Ruppert–Prakash reagent",

abstract = "In the presence of copper thiocyanate, sodium thiocyanate and the inexpensive, easy-to-use trifluoromethylating reagent Me3Si–CF3, diazonium salts are smoothly converted into the corresponding aryl trifluoromethyl thioethers. Combined with diazotisation, this convenient and inexpensive method allows the straightforward synthesis of aryl or heteroaryl trifluoromethyl thioethers from the corresponding anilines.",

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doi = "10.1039/c3sc53076k",

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T1 - Sandmeyer trifluoromethylthiolation of arenediazonium salts with sodium thiocyanate and Ruppert–Prakash reagent

AU - Danoun, Grégory

AU - Bayarmagnai, Bilguun

AU - Gruenberg, Matthias F.

AU - Goossen, Lukas J.

PY - 2014/3/3

Y1 - 2014/3/3

N2 - In the presence of copper thiocyanate, sodium thiocyanate and the inexpensive, easy-to-use trifluoromethylating reagent Me3Si–CF3, diazonium salts are smoothly converted into the corresponding aryl trifluoromethyl thioethers. Combined with diazotisation, this convenient and inexpensive method allows the straightforward synthesis of aryl or heteroaryl trifluoromethyl thioethers from the corresponding anilines.

AB - In the presence of copper thiocyanate, sodium thiocyanate and the inexpensive, easy-to-use trifluoromethylating reagent Me3Si–CF3, diazonium salts are smoothly converted into the corresponding aryl trifluoromethyl thioethers. Combined with diazotisation, this convenient and inexpensive method allows the straightforward synthesis of aryl or heteroaryl trifluoromethyl thioethers from the corresponding anilines.

U2 - 10.1039/c3sc53076k

DO - 10.1039/c3sc53076k

M3 - Article

AN - SCOPUS:84897729940

SN - 2041-6520

VL - 5

SP - 1312

EP - 1316

JO - Chemical Science

JF - Chemical Science

IS - 4

ER -

Sandmeyer trifluoromethylthiolation of arenediazonium salts with sodium thiocyanate and Ruppert–Prakash reagent

Abstract

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