Abstract
Summary: SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli.
| Original language | English |
|---|---|
| Pages (from-to) | 3312-3313 |
| Number of pages | 2 |
| Journal | Bioinformatics |
| Volume | 21 |
| Issue number | 15 |
| DOIs | |
| Publication status | Published - 1 Aug 2005 |
| Externally published | Yes |