TY - JOUR
T1 - Selective Palladium-Catalyzed Domino Heck/Buchwald–Hartwig Arylations of N-Glycosylcinnamamides
T2 - An Efficient Route to 4-Aryl-N-glycosylquinolin-2-ones
AU - Luong, Thi Thanh Huyen
AU - Touchet, Sabrina
AU - Alami, Mouad
AU - Messaoudi, Samir
N1 - Publisher Copyright:
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2017/4/17
Y1 - 2017/4/17
N2 - An efficient and selective domino Heck/Buchwald–Hartwig arylations of readily available N-glycosylcinnamamides with aryl iodides have been established. Using palladium(II) acetate as a catalyst, potassium acetate as the base and tetrabutylamonium bromide as an additive in dioxane, the protocol proved to be general, and a variety of 4-aryl-N-glycosylquinolin-2-ones has been prepared in good yields with exclusive α- or β-selectivity. (Figure presented.).
AB - An efficient and selective domino Heck/Buchwald–Hartwig arylations of readily available N-glycosylcinnamamides with aryl iodides have been established. Using palladium(II) acetate as a catalyst, potassium acetate as the base and tetrabutylamonium bromide as an additive in dioxane, the protocol proved to be general, and a variety of 4-aryl-N-glycosylquinolin-2-ones has been prepared in good yields with exclusive α- or β-selectivity. (Figure presented.).
KW - 4-aryl-N-glycosylquinolin-2-ones
KW - Heck/Buchwald–Hartwig reactions
KW - N-glycosylcinnamamides
KW - palladium catalysis
U2 - 10.1002/adsc.201601382
DO - 10.1002/adsc.201601382
M3 - Article
AN - SCOPUS:85015634257
SN - 1615-4150
VL - 359
SP - 1320
EP - 1330
JO - Advanced Synthesis and Catalysis
JF - Advanced Synthesis and Catalysis
IS - 8
ER -