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Some mathematical models for flagellar activation mechanisms

  • Université Paris-Saclay
  • Institut Universitaire de France
  • International School of Advanced Studies
  • Ecole polytechnique

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

This paper focuses on studying a model for dyneins, cytoskeletal motor proteins responsible for axonemal activity. The model is a coupled system of partial differential equations inspired by [F. Jülicher and J. Prost, Cooperative molecular motors, Phys. Rev. Lett. 75 (1995) 2618–2621; F. Jülicher and J. Prost, Molecular motors: From individual to collective behavior, Prog. Theor. Phys. Suppl. 130 (1998) 9–16] and incorporating two rows of molecular motors between microtubules filaments. Existence and uniqueness of a solution are proved, together with the presence of a supercritical Hopf bifurcation. Additionally, numerical simulations are provided to illustrate the theoretical results. A brief study on the generalization to N-rows is also included.

Original languageEnglish
Pages (from-to)2395-2424
Number of pages30
JournalMathematical Models and Methods in Applied Sciences
Volume35
Issue number11
DOIs
Publication statusPublished - 1 Oct 2025
Externally publishedYes

Keywords

  • Axoneme
  • flagellar modeling
  • numerical simulations
  • partial differential equations
  • supercritical Hopf bifurcation

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