Straightforward four-component access to spiroindolines

Laurent El Kaïm; Laurence Grimaud; Xavier Frédéric Le Goff; Martha Menes-Arzate; Luis D. Miranda

doi:10.1039/c1cc12236c

Straightforward four-component access to spiroindolines

Laurent El Kaïm
, Laurence Grimaud
, Xavier Frédéric Le Goff
, Martha Menes-Arzate
, Luis D. Miranda

Unité Chimie et Procédés
CNRS
Universidad Nacional Autonoma de Mexico
Universidad Nacional Autónoma de México

Research output: Contribution to journal › Article › peer-review

Abstract

Spiroindolines could be synthesized via a very convenient one-pot procedure combining a Ugi coupling and a new copper-catalyzed oxidative process at a peptidyl position. Due to the nature of the first step, this method offers a straightforward access to complex alkaloids with four points of molecular diversity.

Original language	English
Pages (from-to)	8145-8147
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	28
DOIs	https://doi.org/10.1039/c1cc12236c
Publication status	Published - 28 Jul 2011
Externally published	Yes

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title = "Straightforward four-component access to spiroindolines",

abstract = "Spiroindolines could be synthesized via a very convenient one-pot procedure combining a Ugi coupling and a new copper-catalyzed oxidative process at a peptidyl position. Due to the nature of the first step, this method offers a straightforward access to complex alkaloids with four points of molecular diversity.",

author = "\{El Ka{\"i}m\}, Laurent and Laurence Grimaud and \{Le Goff\}, \{Xavier Fr{\'e}d{\'e}ric\} and Martha Menes-Arzate and Miranda, \{Luis D.\}",

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doi = "10.1039/c1cc12236c",

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AU - El Kaïm, Laurent

AU - Grimaud, Laurence

AU - Le Goff, Xavier Frédéric

AU - Menes-Arzate, Martha

AU - Miranda, Luis D.

PY - 2011/7/28

Y1 - 2011/7/28

N2 - Spiroindolines could be synthesized via a very convenient one-pot procedure combining a Ugi coupling and a new copper-catalyzed oxidative process at a peptidyl position. Due to the nature of the first step, this method offers a straightforward access to complex alkaloids with four points of molecular diversity.

AB - Spiroindolines could be synthesized via a very convenient one-pot procedure combining a Ugi coupling and a new copper-catalyzed oxidative process at a peptidyl position. Due to the nature of the first step, this method offers a straightforward access to complex alkaloids with four points of molecular diversity.

U2 - 10.1039/c1cc12236c

DO - 10.1039/c1cc12236c

M3 - Article

C2 - 21674079

AN - SCOPUS:79959875882

SN - 1359-7345

VL - 47

SP - 8145

EP - 8147

JO - Chemical Communications

JF - Chemical Communications

IS - 28

ER -

Straightforward four-component access to spiroindolines

Abstract

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