Synthesis of functionalized 4-phenyl-pyridines via electrochemically prepared organozinc reagents

Erwan Le Gall; Corinne Gosmini; Jean Yves Nédélec; Jacques Périchon

doi:10.1016/S0040-4020(01)00015-1

Synthesis of functionalized 4-phenyl-pyridines via electrochemically prepared organozinc reagents

Erwan Le Gall
, Corinne Gosmini
, Jean Yves Nédélec
, Jacques Périchon

Institut de Chimie et des Matériaux de Paris Est, CNRS UPEC/UMR 7182

Research output: Contribution to journal › Article › peer-review

Abstract

The efficient and convenient synthesis of various functionalized 4-phenyl-pyridines 2 is described. The key step of the procedure is the electrochemical formation of aromatic organozinc reagents 1 and their coupling with pyridinium salts. Intermediate 1,4-dihydropyridines are oxidized using mild conditions to provide functionalized 4-phenyl-pyridines in moderate to high overall yields.

Original language	English
Pages (from-to)	1923-1927
Number of pages	5
Journal	Tetrahedron
Volume	57
Issue number	10
DOIs	https://doi.org/10.1016/S0040-4020(01)00015-1
Publication status	Published - 3 Mar 2001
Externally published	Yes

Keywords

4-phenyl-pyridines
Pyridinium

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10.1016/S0040-4020(01)00015-1

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title = "Synthesis of functionalized 4-phenyl-pyridines via electrochemically prepared organozinc reagents",

abstract = "The efficient and convenient synthesis of various functionalized 4-phenyl-pyridines 2 is described. The key step of the procedure is the electrochemical formation of aromatic organozinc reagents 1 and their coupling with pyridinium salts. Intermediate 1,4-dihydropyridines are oxidized using mild conditions to provide functionalized 4-phenyl-pyridines in moderate to high overall yields.",

keywords = "4-phenyl-pyridines, Pyridinium",

author = "Gall, \{Erwan Le\} and Corinne Gosmini and N{\'e}d{\'e}lec, \{Jean Yves\} and Jacques P{\'e}richon",

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doi = "10.1016/S0040-4020(01)00015-1",

language = "English",

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T1 - Synthesis of functionalized 4-phenyl-pyridines via electrochemically prepared organozinc reagents

AU - Gall, Erwan Le

AU - Gosmini, Corinne

AU - Nédélec, Jean Yves

AU - Périchon, Jacques

PY - 2001/3/3

Y1 - 2001/3/3

N2 - The efficient and convenient synthesis of various functionalized 4-phenyl-pyridines 2 is described. The key step of the procedure is the electrochemical formation of aromatic organozinc reagents 1 and their coupling with pyridinium salts. Intermediate 1,4-dihydropyridines are oxidized using mild conditions to provide functionalized 4-phenyl-pyridines in moderate to high overall yields.

AB - The efficient and convenient synthesis of various functionalized 4-phenyl-pyridines 2 is described. The key step of the procedure is the electrochemical formation of aromatic organozinc reagents 1 and their coupling with pyridinium salts. Intermediate 1,4-dihydropyridines are oxidized using mild conditions to provide functionalized 4-phenyl-pyridines in moderate to high overall yields.

KW - 4-phenyl-pyridines

KW - Pyridinium

UR - https://www.scopus.com/pages/publications/0035799165

U2 - 10.1016/S0040-4020(01)00015-1

DO - 10.1016/S0040-4020(01)00015-1

M3 - Article

AN - SCOPUS:0035799165

SN - 0040-4020

VL - 57

SP - 1923

EP - 1927

JO - Tetrahedron

JF - Tetrahedron

IS - 10

ER -

Synthesis of functionalized 4-phenyl-pyridines via electrochemically prepared organozinc reagents

Abstract

Keywords

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