Abstract
Researchers have long been investigating novel targets for anticancer drugs. Telomeres and telomerase represent, at least in theory, extremely attractive targets in oncology. However, no such molecule has currently obtained approval, and the most advanced compounds are currently in clinical trials. The next few years will be critical for target validation in the clinic. Independent of this outcome, the extreme ends of chromosomes represent a fascinating field of investigation for cell biologists and oncologists.
| Original language | English |
|---|---|
| Title of host publication | Targeted Therapies in Oncology |
| Publisher | CRC Press |
| Pages | 349-374 |
| Number of pages | 26 |
| ISBN (Electronic) | 9781420020588 |
| ISBN (Print) | 9780849393716 |
| Publication status | Published - 1 Jan 2007 |
| Externally published | Yes |