@inbook{ada98893e8ba43d2b5d99e3e9486cb66,
title = "Tetramolecular quadruplex stability and assembly",
abstract = "Guanine quadruplexes (G4) are unusual four-stranded nucleic acid structures formed by G-rich DNA/RNA. Beyond their likely biological relevance, the self-assembly, stability, and rigidity of these structures are also interesting for nanotechnology and biotechnology applications. Therefore, efforts are carried out to understand the rules that govern stability and folding of G-quadruplexes. We focus this chapter on tetramolecular conformations which are simple tractable models. We report here the experimental parameters, molecules, and modifications that affect thermal stability and/or association kinetics of these structures. Some chemical modifications which facilitate tetramolecular quadruplex formation and can be useful for nano- or biotechnology are also described.",
keywords = "Association kinetics, Chemical modifications, Nanotechnology and biotechnology applications, Tetramolecular quadruplexes, Thermal stability",
author = "Tran, \{Phong Lan Thao\} and \{De Cian\}, Anne and Julien Gros and Rui Moriyama and Mergny, \{Jean Louis\}",
note = "Funding Information: This work has been supported by ANR (QuantADN, F-DNA and G4-Toolbox), Conseil R{\'e}gional d{\textquoteright}Aquitaine, ARC and FRM. We would like to thank all our collaborators, past and present, for helpful discussions.",
year = "2013",
month = apr,
day = "11",
doi = "10.1007/128-2012-334",
language = "English",
isbn = "9783642347429",
series = "Topics in Current Chemistry",
pages = "243--274",
editor = "Chaires, \{Jonathan B.\} and David Graves",
booktitle = "Quadruplex Nucleic Acids",
}