The cell: A chemical analog calculator

François Fages, Franck Molina

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

A cell processes the information of the chemical signals it receives from its environment by performing noise filtering, signal amplification and often analog-digital conversion functions to produce all-or-nothing responses. This chapter shows how the Turing-completeness proof of continuous chemical reaction networks (CRNs) over a finite number of molecular species proposes the bases of such a reconciliation, without artificial construction, with capabilities for both analysis of natural chemical programs in living cells and synthesis of artificial chemical programs in non-living vesicles. CRNs are a basic formalism in chemistry and biology for describing complex systems of molecular interactions. The Church-Turing thesis states that there is only one notion of effective computation over discrete data structures, and by extension over arbitrary-precision real numbers.

Original languageEnglish
Title of host publicationSymbolic Approaches to Modeling and Analysis of Biological Systems
Publisherwiley
Pages235-254
Number of pages20
ISBN (Electronic)9781394229086
ISBN (Print)9781789450293
DOIs
Publication statusPublished - 8 Aug 2023
Externally publishedYes

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