The invention of radical reactions. Part XVII. A decarboxylative sulphonylation of carboxylic acids

Derek H.R. Barton; Brigitte Lacher; Boguslaw Misterkiewicz; Samir Z. Zard

doi:10.1016/S0040-4020(01)85895-6

The invention of radical reactions. Part XVII. A decarboxylative sulphonylation of carboxylic acids

Derek H.R. Barton
, Brigitte Lacher
, Boguslaw Misterkiewicz
, Samir Z. Zard

Institut de Chimie des Substances Naturelles

Research output: Contribution to journal › Article › peer-review

Abstract

Irradiation with visible light of N-hydroxy-2-thiopyridone esters 1 in the presence of sulphur dioxide gave the corresponding thiosulphonates 4 in good yield. These could be converted to sulphones 5 by treatment with KOH and an alkylating agent. Alternatively, exposure to sulphuryl chloride followed by a primary or secondary amine afforded sulphonamides 6.

Original language	English
Pages (from-to)	1153-1158
Number of pages	6
Journal	Tetrahedron
Volume	44
Issue number	4
DOIs	https://doi.org/10.1016/S0040-4020(01)85895-6
Publication status	Published - 1 Jan 1988
Externally published	Yes

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10.1016/S0040-4020(01)85895-6

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title = "The invention of radical reactions. Part XVII. A decarboxylative sulphonylation of carboxylic acids",

abstract = "Irradiation with visible light of N-hydroxy-2-thiopyridone esters 1 in the presence of sulphur dioxide gave the corresponding thiosulphonates 4 in good yield. These could be converted to sulphones 5 by treatment with KOH and an alkylating agent. Alternatively, exposure to sulphuryl chloride followed by a primary or secondary amine afforded sulphonamides 6.",

author = "Barton, \{Derek H.R.\} and Brigitte Lacher and Boguslaw Misterkiewicz and Zard, \{Samir Z.\}",

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doi = "10.1016/S0040-4020(01)85895-6",

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AU - Barton, Derek H.R.

AU - Lacher, Brigitte

AU - Misterkiewicz, Boguslaw

AU - Zard, Samir Z.

PY - 1988/1/1

Y1 - 1988/1/1

N2 - Irradiation with visible light of N-hydroxy-2-thiopyridone esters 1 in the presence of sulphur dioxide gave the corresponding thiosulphonates 4 in good yield. These could be converted to sulphones 5 by treatment with KOH and an alkylating agent. Alternatively, exposure to sulphuryl chloride followed by a primary or secondary amine afforded sulphonamides 6.

AB - Irradiation with visible light of N-hydroxy-2-thiopyridone esters 1 in the presence of sulphur dioxide gave the corresponding thiosulphonates 4 in good yield. These could be converted to sulphones 5 by treatment with KOH and an alkylating agent. Alternatively, exposure to sulphuryl chloride followed by a primary or secondary amine afforded sulphonamides 6.

U2 - 10.1016/S0040-4020(01)85895-6

DO - 10.1016/S0040-4020(01)85895-6

M3 - Article

AN - SCOPUS:0000038963

SN - 0040-4020

VL - 44

SP - 1153

EP - 1158

JO - Tetrahedron

JF - Tetrahedron

IS - 4

ER -

The invention of radical reactions. Part XVII. A decarboxylative sulphonylation of carboxylic acids

Abstract

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