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The Ugi Reaction of Cyanoacetic Acid as a Route to Tetramic Acid Derivatives

  • Nancy V. Alvarez-Rodríguez
  • , Aurélie Dos Santos
  • , Laurent El Kaïm
  • , Rocío Gámez-Montaño

Research output: Contribution to journalArticlepeer-review

Abstract

Ugi adducts of cyanoacetic acid and aromatic aldehydes are readily cyclized under basic conditions leading to one-pot formation of aminopyrrolinone derivatives.

Original languageEnglish
Article numberst-2015-d0325-l
Pages (from-to)2253-2256
Number of pages4
JournalSynlett
Volume26
Issue number16
DOIs
Publication statusPublished - 1 Oct 2015
Externally publishedYes

Keywords

  • Ugi
  • aminopyrolidinones
  • cyanoacetic
  • isocyanide

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