The use of hydrazones for efficient mannich type coupling with aldehydes and secondary amines

Research output: Contribution to journalArticlepeer-review

Abstract

The Mannich reaction of hydrazones originally limited to the coupling of hydrazones with formaldehyde has been extended to a large variety of aldehydes through appropriate selection of experimental conditions; in conjunction with the Japp-Klingmann reaction, this process provides an efficient synthetic tool for the formation of carbon-carbon bonds.

Original languageEnglish
Pages (from-to)1585-1586
Number of pages2
JournalChemical Communications
Issue number17
DOIs
Publication statusPublished - 7 Sept 2000
Externally publishedYes

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