Three-component Ugi-Smiles couplings of cyclic imines

Laurent El Kaïm; Laurence Grimaud; Julie Oble; Simon Wagschal

doi:10.1016/j.tetlet.2009.01.145

Three-component Ugi-Smiles couplings of cyclic imines

Laurent El Kaïm
, Laurence Grimaud
, Julie Oble
, Simon Wagschal

Unité Chimie et Procédés

Research output: Contribution to journal › Article › peer-review

Abstract

Cyclic imines react with isocyanides and electron-deficient phenols to afford N-aryl piperidines and pyrrolidines in good yields (Ugi-Smiles couplings of cyclic imines). The starting imines were formed by oxidation with N-chlorosuccinimide followed by a base-induced dehydrochlorination.

Original language	English
Pages (from-to)	1741-1743
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	15
DOIs	https://doi.org/10.1016/j.tetlet.2009.01.145
Publication status	Published - 15 Apr 2009
Externally published	Yes

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10.1016/j.tetlet.2009.01.145

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title = "Three-component Ugi-Smiles couplings of cyclic imines",

abstract = "Cyclic imines react with isocyanides and electron-deficient phenols to afford N-aryl piperidines and pyrrolidines in good yields (Ugi-Smiles couplings of cyclic imines). The starting imines were formed by oxidation with N-chlorosuccinimide followed by a base-induced dehydrochlorination.",

author = "Ka{\"i}m, \{Laurent El\} and Laurence Grimaud and Julie Oble and Simon Wagschal",

year = "2009",

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language = "English",

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T1 - Three-component Ugi-Smiles couplings of cyclic imines

AU - Kaïm, Laurent El

AU - Grimaud, Laurence

AU - Oble, Julie

AU - Wagschal, Simon

PY - 2009/4/15

Y1 - 2009/4/15

N2 - Cyclic imines react with isocyanides and electron-deficient phenols to afford N-aryl piperidines and pyrrolidines in good yields (Ugi-Smiles couplings of cyclic imines). The starting imines were formed by oxidation with N-chlorosuccinimide followed by a base-induced dehydrochlorination.

AB - Cyclic imines react with isocyanides and electron-deficient phenols to afford N-aryl piperidines and pyrrolidines in good yields (Ugi-Smiles couplings of cyclic imines). The starting imines were formed by oxidation with N-chlorosuccinimide followed by a base-induced dehydrochlorination.

UR - https://www.scopus.com/pages/publications/60649095384

U2 - 10.1016/j.tetlet.2009.01.145

DO - 10.1016/j.tetlet.2009.01.145

M3 - Article

AN - SCOPUS:60649095384

SN - 0040-4039

VL - 50

SP - 1741

EP - 1743

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 15

ER -

Three-component Ugi-Smiles couplings of cyclic imines

Abstract

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