Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands

Jun Zhou; Anne Bourdoncle; Frédéric Rosu; Valérie Gabelica; Jean Louis Mergny

doi:10.1002/anie.201205390

Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands

Jun Zhou
, Anne Bourdoncle
, Frédéric Rosu
, Valérie Gabelica
, Jean Louis Mergny

Univ. Bordeaux
INSERM, U869, IECB
University of Liège
Univ. Poitiers

Research output: Contribution to journal › Article › peer-review

65 Citations (Scopus)

Abstract

In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li⁺ ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na⁺ ions and characterized by gel electrophoresis and spectroscopy.

Original language	English
Pages (from-to)	11002-11005
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	44
DOIs	https://doi.org/10.1002/anie.201205390
Publication status	Published - 29 Oct 2012
Externally published	Yes

Keywords

DNA
G-quadruplexes
circular dichroism
electrospray mass spectrometry
nucleic acids

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10.1002/anie.201205390

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abstract = "In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li+ ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na+ ions and characterized by gel electrophoresis and spectroscopy.",

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author = "Jun Zhou and Anne Bourdoncle and Fr{\'e}d{\'e}ric Rosu and Val{\'e}rie Gabelica and Mergny, \{Jean Louis\}",

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AU - Gabelica, Valérie

AU - Mergny, Jean Louis

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KW - DNA

KW - G-quadruplexes

KW - circular dichroism

KW - electrospray mass spectrometry

KW - nucleic acids

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DO - 10.1002/anie.201205390

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Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands

Abstract

Keywords

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