Ugi-Smiles couplings of 4-substituted pyridine derivatives: A fast access to chloroquine analogues

Laurent El Kaïm; Laurence Grimaud; Patil Pravin

doi:10.1021/ol202974w

Ugi-Smiles couplings of 4-substituted pyridine derivatives: A fast access to chloroquine analogues

Laurent El Kaïm
, Laurence Grimaud
, Patil Pravin

Unité Chimie et Procédés

Research output: Contribution to journal › Article › peer-review

Abstract

4-Hydroxy and mercapto pyridines were successfully tested in Ugi-Smiles couplings. Such multicomponent reactions applied to quinoline derivatives afford a very convenient and short synthesis of antimalarial analogues.

Original language	English
Pages (from-to)	476-478
Number of pages	3
Journal	Organic Letters
Volume	14
Issue number	2
DOIs	https://doi.org/10.1021/ol202974w
Publication status	Published - 20 Jan 2012
Externally published	Yes

Access to Document

10.1021/ol202974w

Cite this

@article{5a591f06f154426a8a6ed36bc8c60e6c,

title = "Ugi-Smiles couplings of 4-substituted pyridine derivatives: A fast access to chloroquine analogues",

abstract = "4-Hydroxy and mercapto pyridines were successfully tested in Ugi-Smiles couplings. Such multicomponent reactions applied to quinoline derivatives afford a very convenient and short synthesis of antimalarial analogues.",

author = "\{El Ka{\"i}m\}, Laurent and Laurence Grimaud and Patil Pravin",

year = "2012",

month = jan,

day = "20",

doi = "10.1021/ol202974w",

language = "English",

volume = "14",

pages = "476--478",

journal = "Organic Letters",

issn = "1523-7060",

number = "2",

}

TY - JOUR

T1 - Ugi-Smiles couplings of 4-substituted pyridine derivatives

T2 - A fast access to chloroquine analogues

AU - El Kaïm, Laurent

AU - Grimaud, Laurence

AU - Pravin, Patil

PY - 2012/1/20

Y1 - 2012/1/20

N2 - 4-Hydroxy and mercapto pyridines were successfully tested in Ugi-Smiles couplings. Such multicomponent reactions applied to quinoline derivatives afford a very convenient and short synthesis of antimalarial analogues.

AB - 4-Hydroxy and mercapto pyridines were successfully tested in Ugi-Smiles couplings. Such multicomponent reactions applied to quinoline derivatives afford a very convenient and short synthesis of antimalarial analogues.

U2 - 10.1021/ol202974w

DO - 10.1021/ol202974w

M3 - Article

C2 - 22206231

AN - SCOPUS:84856096786

SN - 1523-7060

VL - 14

SP - 476

EP - 478

JO - Organic Letters

JF - Organic Letters

IS - 2

ER -

Ugi-Smiles couplings of 4-substituted pyridine derivatives: A fast access to chloroquine analogues

Abstract

Access to Document

Fingerprint

Cite this