Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS

Natacha Bonneau; Isabelle Schmitz-Afonso; Alain Brunelle; David Touboul; Pierre Champy

doi:10.1016/j.dib.2016.04.067

Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS

Natacha Bonneau
, Isabelle Schmitz-Afonso
, Alain Brunelle
, David Touboul
, Pierre Champy

Université Paris-Sud
Institut de Chimie des Substances Naturelles
Université de Rouen

Research output: Contribution to journal › Article › peer-review

Abstract

Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was performed by UPLC-MS/MS in selected reaction monitoring (SRM) mode, using a triple quadrupole mass analyzer. A natural analog of annonacin was used as an internal standard. Analyzed data set of the analytical validation of this method is presented, including stability of the samples, extraction recovery and matrix effect, supporting the results described in the article "Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS" N. Bonneau, I. Schmitz-Afonso, D. Touboul, A. Brunelle, P. Champy (2016) [1].

Original language	English
Pages (from-to)	1633-1638
Number of pages	6
Journal	Data in Brief
Volume	7
DOIs	https://doi.org/10.1016/j.dib.2016.04.067
Publication status	Published - 1 Jun 2016
Externally published	Yes

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title = "Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS",

abstract = "Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was performed by UPLC-MS/MS in selected reaction monitoring (SRM) mode, using a triple quadrupole mass analyzer. A natural analog of annonacin was used as an internal standard. Analyzed data set of the analytical validation of this method is presented, including stability of the samples, extraction recovery and matrix effect, supporting the results described in the article {"}Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS{"} N. Bonneau, I. Schmitz-Afonso, D. Touboul, A. Brunelle, P. Champy (2016) [1].",

author = "Natacha Bonneau and Isabelle Schmitz-Afonso and Alain Brunelle and David Touboul and Pierre Champy",

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doi = "10.1016/j.dib.2016.04.067",

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T1 - Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS

AU - Bonneau, Natacha

AU - Schmitz-Afonso, Isabelle

AU - Brunelle, Alain

AU - Touboul, David

AU - Champy, Pierre

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was performed by UPLC-MS/MS in selected reaction monitoring (SRM) mode, using a triple quadrupole mass analyzer. A natural analog of annonacin was used as an internal standard. Analyzed data set of the analytical validation of this method is presented, including stability of the samples, extraction recovery and matrix effect, supporting the results described in the article "Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS" N. Bonneau, I. Schmitz-Afonso, D. Touboul, A. Brunelle, P. Champy (2016) [1].

AB - Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was performed by UPLC-MS/MS in selected reaction monitoring (SRM) mode, using a triple quadrupole mass analyzer. A natural analog of annonacin was used as an internal standard. Analyzed data set of the analytical validation of this method is presented, including stability of the samples, extraction recovery and matrix effect, supporting the results described in the article "Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS" N. Bonneau, I. Schmitz-Afonso, D. Touboul, A. Brunelle, P. Champy (2016) [1].

UR - https://www.scopus.com/pages/publications/84965156994

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DO - 10.1016/j.dib.2016.04.067

M3 - Article

AN - SCOPUS:84965156994

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SP - 1633

EP - 1638

JO - Data in Brief

JF - Data in Brief

ER -

Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS

Abstract

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