Variance reduction result for a projected adaptive biasing force method

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Abstract

This paper is committed to investigate an extension of the classical adaptive biasing force method, which is used to compute the free energy related to the Boltzmann-Gibbs measure and a reaction coordinate function. The issue of this technique is that the approximated gradient of the free energy, called biasing force, is not a gradient. The commitment to this field is to project the estimated biasing force on a gradient using the Helmholtz decomposition. The variance of the biasing force is reduced using this technique, which makes the algorithm more efficient than the standard ABF method. We prove exponential convergence to equilibrium of the estimated free energy, with a precise rate of convergence in function of Logarithmic Sobolev inequality constants.

Original languageEnglish
Title of host publicationComputational Mathematics, Numerical Analysis and Applications - Lecture Notes of the XVII ‘Jacques-Louis Lions’ Spanish-French School
EditorsMariano Mateos, Pedro Alonso
PublisherSpringer International Publishing
Pages221-227
Number of pages7
ISBN (Print)9783319496306
DOIs
Publication statusPublished - 1 Jan 2017
Event17th 'Jacques-Louis Lions' Spanish-French School on Computational Mathematics, Numerical Analysis and Applications, 2016 - Gijon, Spain
Duration: 6 Jun 201610 Jun 2016

Publication series

NameSEMA SIMAI Springer Series
Volume13
ISSN (Print)2199-3041
ISSN (Electronic)2199-305X

Conference

Conference17th 'Jacques-Louis Lions' Spanish-French School on Computational Mathematics, Numerical Analysis and Applications, 2016
Country/TerritorySpain
CityGijon
Period6/06/1610/06/16

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