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White matter fiber segmentation using functional varifolds

  • Kuldeep Kumar
  • , Pietro Gori
  • , Benjamin Charlier
  • , Stanley Durrleman
  • , Olivier Colliot
  • , Christian Desrosiers
  • Department of Electrical Engineering, Ecole de Technologie Supérieure
  • Sorbonne Université
  • CNRS LTCI
  • University of Montpellier (UMR MiVEGEC)
  • AP-HP

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The extraction of fibers from dMRI data typically produces a large number of fibers, it is common to group fibers into bundles. To this end, many specialized distance measures, such as MCP, have been used for fiber similarity. However, these distance based approaches require point-wise correspondence and focus only on the geometry of the fibers. Recent publications have highlighted that using microstructure measures along fibers improves tractography analysis. Also, many neurodegenerative diseases impacting white matter require the study of microstructure measures as well as the white matter geometry. Motivated by these, we propose to use a novel computational model for fibers, called functional varifolds, characterized by a metric that considers both the geometry and microstructure measure (e.g. GFA) along the fiber pathway. We use it to cluster fibers with a dictionary learning and sparse coding-based framework, and present a preliminary analysis using HCP data.

Original languageEnglish
Title of host publicationGraphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics - 1st International Workshop, GRAIL 2017 6th International Workshop, MFCA 2017 and 3rd International Workshop, MICGen 2017 Held in Conjunction with MICCAI 2017, Proceedings
EditorsM. Jorge Cardoso, Tal Arbel
PublisherSpringer Verlag
Pages92-100
Number of pages9
ISBN (Print)9783319676746
DOIs
Publication statusPublished - 1 Jan 2017
Event1st International Workshop on Graphs in Biomedical Image Analysis, GRAIL 2017, 6th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2017 and 3rd International Workshop on Imaging Genetics, MICGen 2017 held in Conjunction with 20th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2017 - Quebec City, Canada
Duration: 10 Sept 201714 Sept 2017

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume10551 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference1st International Workshop on Graphs in Biomedical Image Analysis, GRAIL 2017, 6th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2017 and 3rd International Workshop on Imaging Genetics, MICGen 2017 held in Conjunction with 20th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2017
Country/TerritoryCanada
CityQuebec City
Period10/09/1714/09/17

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