A convergent approach to functionalised alkynes

Jean Boivin; Sylvain Huppé; Samir Z. Zard

doi:10.1016/S0040-4039(96)02015-1

A convergent approach to functionalised alkynes

Jean Boivin
, Sylvain Huppé
, Samir Z. Zard

Laboratoire de Synthèse Organique

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

Knoevenagel type condensation of 4-unsubstituted isoxazolinones with ketones or aldehydes followed by Michael addition of a nucleophile - hydride, cyanide, or phosphite - and exposure of the adduct to sodium nitrite/aqueous acetic acid and ferrous sulfate gives variously functionalised alkynes.

langue originale	Anglais
Pages (de - à)	8735-8738
Nombre de pages	4
journal	Tetrahedron Letters
Volume	37
Numéro de publication	48
Les DOIs	https://doi.org/10.1016/S0040-4039(96)02015-1
état	Publié - 25 nov. 1996

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10.1016/S0040-4039(96)02015-1

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@article{384c05b4210d410587efecf81924b7eb,

title = "A convergent approach to functionalised alkynes",

abstract = "Knoevenagel type condensation of 4-unsubstituted isoxazolinones with ketones or aldehydes followed by Michael addition of a nucleophile - hydride, cyanide, or phosphite - and exposure of the adduct to sodium nitrite/aqueous acetic acid and ferrous sulfate gives variously functionalised alkynes.",

author = "Jean Boivin and Sylvain Hupp{\'e} and Zard, \{Samir Z.\}",

year = "1996",

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T1 - A convergent approach to functionalised alkynes

AU - Boivin, Jean

AU - Huppé, Sylvain

AU - Zard, Samir Z.

PY - 1996/11/25

Y1 - 1996/11/25

N2 - Knoevenagel type condensation of 4-unsubstituted isoxazolinones with ketones or aldehydes followed by Michael addition of a nucleophile - hydride, cyanide, or phosphite - and exposure of the adduct to sodium nitrite/aqueous acetic acid and ferrous sulfate gives variously functionalised alkynes.

AB - Knoevenagel type condensation of 4-unsubstituted isoxazolinones with ketones or aldehydes followed by Michael addition of a nucleophile - hydride, cyanide, or phosphite - and exposure of the adduct to sodium nitrite/aqueous acetic acid and ferrous sulfate gives variously functionalised alkynes.

UR - https://www.scopus.com/pages/publications/0030602161

U2 - 10.1016/S0040-4039(96)02015-1

DO - 10.1016/S0040-4039(96)02015-1

M3 - Article

AN - SCOPUS:0030602161

SN - 0040-4039

VL - 37

SP - 8735

EP - 8738

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 48

ER -

A convergent approach to functionalised alkynes

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