A practical source of chlorodifluoromethyl radicals. Convergent routes to gem -difluoroalkenes and -dienes and (2,2-Difluoroethyl)-indoles, -azaindoles, and -naphthols

Pierre Salomon; Samir Z. Zard

doi:10.1021/ol501063a

A practical source of chlorodifluoromethyl radicals. Convergent routes to gem -difluoroalkenes and -dienes and (2,2-Difluoroethyl)-indoles, -azaindoles, and -naphthols

Pierre Salomon
, Samir Z. Zard

Laboratoire de Synthèse Organique

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

46 Citations (Scopus)

Résumé

The preparation of O-octadecyl-S-chlorodifluoromethyl xanthate from chlorodifluoroacetic acid and its use as a convenient source of chlordifluoromethyl radicals is described. This reagent may be used to access gem-difluoroalkenes and -dienes, as well as (2,2-difluoroethyl)indolines, -indoles, and -naphthols.

langue originale	Anglais
Pages (de - à)	2926-2929
Nombre de pages	4
journal	Organic Letters
Volume	16
Numéro de publication	11
Les DOIs	https://doi.org/10.1021/ol501063a
état	Publié - 6 juin 2014
Modification externe	Oui

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10.1021/ol501063a

Contient cette citation

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title = "A practical source of chlorodifluoromethyl radicals. Convergent routes to gem -difluoroalkenes and -dienes and (2,2-Difluoroethyl)-indoles, -azaindoles, and -naphthols",

abstract = "The preparation of O-octadecyl-S-chlorodifluoromethyl xanthate from chlorodifluoroacetic acid and its use as a convenient source of chlordifluoromethyl radicals is described. This reagent may be used to access gem-difluoroalkenes and -dienes, as well as (2,2-difluoroethyl)indolines, -indoles, and -naphthols.",

author = "Pierre Salomon and Zard, \{Samir Z.\}",

year = "2014",

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doi = "10.1021/ol501063a",

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journal = "Organic Letters",

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T1 - A practical source of chlorodifluoromethyl radicals. Convergent routes to gem -difluoroalkenes and -dienes and (2,2-Difluoroethyl)-indoles, -azaindoles, and -naphthols

AU - Salomon, Pierre

AU - Zard, Samir Z.

PY - 2014/6/6

Y1 - 2014/6/6

N2 - The preparation of O-octadecyl-S-chlorodifluoromethyl xanthate from chlorodifluoroacetic acid and its use as a convenient source of chlordifluoromethyl radicals is described. This reagent may be used to access gem-difluoroalkenes and -dienes, as well as (2,2-difluoroethyl)indolines, -indoles, and -naphthols.

AB - The preparation of O-octadecyl-S-chlorodifluoromethyl xanthate from chlorodifluoroacetic acid and its use as a convenient source of chlordifluoromethyl radicals is described. This reagent may be used to access gem-difluoroalkenes and -dienes, as well as (2,2-difluoroethyl)indolines, -indoles, and -naphthols.

U2 - 10.1021/ol501063a

DO - 10.1021/ol501063a

M3 - Article

AN - SCOPUS:84902096263

SN - 1523-7060

VL - 16

SP - 2926

EP - 2929

JO - Organic Letters

JF - Organic Letters

IS - 11

ER -

A practical source of chlorodifluoromethyl radicals. Convergent routes to gem -difluoroalkenes and -dienes and (2,2-Difluoroethyl)-indoles, -azaindoles, and -naphthols

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