Apport de l'imagerie par spectrométrie de masse pour l'analyse directe du globotriaosylcéramide et du galabiosylcéramide tissulaires

Sandrine Roy; David Touboul; Alain Brunelle; Dominique P. Germain; Olivier Laprévote; Pierre Chaminade

doi:10.1051/medsci/20052111s55

Apport de l'imagerie par spectrométrie de masse pour l'analyse directe du globotriaosylcéramide et du galabiosylcéramide tissulaires

Sandrine Roy
, David Touboul
, Alain Brunelle
, Dominique P. Germain
, Olivier Laprévote
, Pierre Chaminade

Faculté de Pharmacie Paris XI
Institut de Chimie des Substances Naturelles
Pôle de Biologie

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

In Fabry disease, accumulation of globotrianosylceramide and galabiosylceramide are observed by coloration methods associated to optic or electron microscopy. But a new technology, imaging mass spectrometry, may be applied to the analysis of these metabolites in tissue of hemizygous patients with Fabry disease. Advantages and disavantadges of this technic are discussed.

Titre traduit de la contribution	Imaging mass spectrometry and direct analysis of globotriaosylceramide and galabiosylceramide in tissue
langue originale	Français
Pages (de - à)	55-56
Nombre de pages	2
journal	Medecine/Sciences
Volume	21
Numéro de publication	SPEC. ISS. NOV.
Les DOIs	https://doi.org/10.1051/medsci/20052111s55
état	Publié - 1 janv. 2005
Modification externe	Oui

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10.1051/medsci/20052111s55

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abstract = "In Fabry disease, accumulation of globotrianosylceramide and galabiosylceramide are observed by coloration methods associated to optic or electron microscopy. But a new technology, imaging mass spectrometry, may be applied to the analysis of these metabolites in tissue of hemizygous patients with Fabry disease. Advantages and disavantadges of this technic are discussed.",

author = "Sandrine Roy and David Touboul and Alain Brunelle and Germain, \{Dominique P.\} and Olivier Lapr{\'e}vote and Pierre Chaminade",

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AU - Roy, Sandrine

AU - Touboul, David

AU - Brunelle, Alain

AU - Germain, Dominique P.

AU - Laprévote, Olivier

AU - Chaminade, Pierre

PY - 2005/1/1

Y1 - 2005/1/1

N2 - In Fabry disease, accumulation of globotrianosylceramide and galabiosylceramide are observed by coloration methods associated to optic or electron microscopy. But a new technology, imaging mass spectrometry, may be applied to the analysis of these metabolites in tissue of hemizygous patients with Fabry disease. Advantages and disavantadges of this technic are discussed.

AB - In Fabry disease, accumulation of globotrianosylceramide and galabiosylceramide are observed by coloration methods associated to optic or electron microscopy. But a new technology, imaging mass spectrometry, may be applied to the analysis of these metabolites in tissue of hemizygous patients with Fabry disease. Advantages and disavantadges of this technic are discussed.

U2 - 10.1051/medsci/20052111s55

DO - 10.1051/medsci/20052111s55

M3 - Article

AN - SCOPUS:29944435231

SN - 0767-0974

VL - 21

SP - 55

EP - 56

JO - Medecine/Sciences

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IS - SPEC. ISS. NOV.

ER -

Apport de l'imagerie par spectrométrie de masse pour l'analyse directe du globotriaosylcéramide et du galabiosylcéramide tissulaires

Résumé

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