Chemoselective Reduction: Xanthates as Traceless Precursors of Polyfunctionalized α,α-Dichloroketones

Lucile Anthore-Dalion; Samir Z. Zard

doi:10.1021/acs.orglett.7b02636

Chemoselective Reduction: Xanthates as Traceless Precursors of Polyfunctionalized α,α-Dichloroketones

Lucile Anthore-Dalion
, Samir Z. Zard

Laboratoire de Synthèse Organique

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

14 Citations (Scopus)

Résumé

The use of BEt₃·H₂O has allowed the chemoselective reductive dexanthylation in the presence of the very fragile α,α-dichloroketone motif. This has solved a major hurdle in our approach to this important, but hitherto grossly understudied, family of compounds and opened access to a number of very useful synthetic transformations.

langue originale	Anglais
Pages (de - à)	5545-5548
Nombre de pages	4
journal	Organic Letters
Volume	19
Numéro de publication	20
Les DOIs	https://doi.org/10.1021/acs.orglett.7b02636
état	Publié - 20 oct. 2017
Modification externe	Oui

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10.1021/acs.orglett.7b02636

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title = "Chemoselective Reduction: Xanthates as Traceless Precursors of Polyfunctionalized α,α-Dichloroketones",

abstract = "The use of BEt3·H2O has allowed the chemoselective reductive dexanthylation in the presence of the very fragile α,α-dichloroketone motif. This has solved a major hurdle in our approach to this important, but hitherto grossly understudied, family of compounds and opened access to a number of very useful synthetic transformations.",

author = "Lucile Anthore-Dalion and Zard, \{Samir Z.\}",

note = "Publisher Copyright: {\textcopyright} 2017 American Chemical Society.",

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T1 - Chemoselective Reduction

T2 - Xanthates as Traceless Precursors of Polyfunctionalized α,α-Dichloroketones

AU - Anthore-Dalion, Lucile

AU - Zard, Samir Z.

PY - 2017/10/20

Y1 - 2017/10/20

N2 - The use of BEt3·H2O has allowed the chemoselective reductive dexanthylation in the presence of the very fragile α,α-dichloroketone motif. This has solved a major hurdle in our approach to this important, but hitherto grossly understudied, family of compounds and opened access to a number of very useful synthetic transformations.

AB - The use of BEt3·H2O has allowed the chemoselective reductive dexanthylation in the presence of the very fragile α,α-dichloroketone motif. This has solved a major hurdle in our approach to this important, but hitherto grossly understudied, family of compounds and opened access to a number of very useful synthetic transformations.

U2 - 10.1021/acs.orglett.7b02636

DO - 10.1021/acs.orglett.7b02636

M3 - Article

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AN - SCOPUS:85031807809

SN - 1523-7060

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SP - 5545

EP - 5548

JO - Organic Letters

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IS - 20

ER -

Chemoselective Reduction: Xanthates as Traceless Precursors of Polyfunctionalized α,α-Dichloroketones

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