Cobalt-Catalyzed Carbozincation of Ynamides

Romain Sallio; Martin Corpet; Loic Habert; Muriel Durandetti; Corinne Gosmini; Isabelle Gillaizeau

doi:10.1021/acs.joc.6b02612

Cobalt-Catalyzed Carbozincation of Ynamides

Romain Sallio
, Martin Corpet
, Loic Habert
, Muriel Durandetti
, Corinne Gosmini
, Isabelle Gillaizeau

conventionnée avec l'Université d'Orléans
Université Paris-Saclay
Normandie Université

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

33 Citations (Scopus)

Résumé

An original cobalt-catalyzed ynamide carbozincation leading mainly to diverse 3-aryl enamides with mild reaction conditions and good functional-group tolerance has been developed. This reaction displays an excellent regio- and total stereoselectivity and opens the way to appealing synthetic applications. Moreover, this approach allows the selective synthesis of biologically relevant 3,5-disubstituted oxazolone frameworks.

langue originale	Anglais
Pages (de - à)	1254-1259
Nombre de pages	6
journal	Journal of Organic Chemistry
Volume	82
Numéro de publication	2
Les DOIs	https://doi.org/10.1021/acs.joc.6b02612
état	Publié - 20 janv. 2017
Modification externe	Oui

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10.1021/acs.joc.6b02612

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title = "Cobalt-Catalyzed Carbozincation of Ynamides",

abstract = "An original cobalt-catalyzed ynamide carbozincation leading mainly to diverse 3-aryl enamides with mild reaction conditions and good functional-group tolerance has been developed. This reaction displays an excellent regio- and total stereoselectivity and opens the way to appealing synthetic applications. Moreover, this approach allows the selective synthesis of biologically relevant 3,5-disubstituted oxazolone frameworks.",

author = "Romain Sallio and Martin Corpet and Loic Habert and Muriel Durandetti and Corinne Gosmini and Isabelle Gillaizeau",

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AU - Sallio, Romain

AU - Corpet, Martin

AU - Habert, Loic

AU - Durandetti, Muriel

AU - Gosmini, Corinne

AU - Gillaizeau, Isabelle

PY - 2017/1/20

Y1 - 2017/1/20

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AB - An original cobalt-catalyzed ynamide carbozincation leading mainly to diverse 3-aryl enamides with mild reaction conditions and good functional-group tolerance has been developed. This reaction displays an excellent regio- and total stereoselectivity and opens the way to appealing synthetic applications. Moreover, this approach allows the selective synthesis of biologically relevant 3,5-disubstituted oxazolone frameworks.

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Cobalt-Catalyzed Carbozincation of Ynamides

Résumé

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