Cs 2CO 3 in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions

Sophian Sahnoun; Samir Messaoudi; Jean François Peyrat; Jean Daniel Brion; Mouad Alami

doi:10.1016/j.tetlet.2012.03.117

Cs ₂CO ₃ in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions

Sophian Sahnoun
, Samir Messaoudi
, Jean François Peyrat
, Jean Daniel Brion
, Mouad Alami

Univ Paris-Sud
Université Paris-Saclay

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

16 Citations (Scopus)

Résumé

An efficient hydration reaction of various (hetero)aryl nitriles using Cs ₂CO ₃ in pyrrolidinone is described. This new metal-free protocol proved to be highly effective and general to synthesize a variety of (hetero)aryl amides.

langue originale	Anglais
Pages (de - à)	2860-2863
Nombre de pages	4
journal	Tetrahedron Letters
Volume	53
Numéro de publication	23
Les DOIs	https://doi.org/10.1016/j.tetlet.2012.03.117
état	Publié - 6 juin 2012
Modification externe	Oui

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10.1016/j.tetlet.2012.03.117

Contient cette citation

@article{2b60e02752fc45e583582104c77d6a4e,

title = "Cs 2CO 3 in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions",

abstract = "An efficient hydration reaction of various (hetero)aryl nitriles using Cs 2CO 3 in pyrrolidinone is described. This new metal-free protocol proved to be highly effective and general to synthesize a variety of (hetero)aryl amides.",

keywords = "Amides, Hydration, Metal-free procedure, Nitriles",

author = "Sophian Sahnoun and Samir Messaoudi and Peyrat, \{Jean Fran{\c c}ois\} and Brion, \{Jean Daniel\} and Mouad Alami",

year = "2012",

month = jun,

day = "6",

doi = "10.1016/j.tetlet.2012.03.117",

language = "English",

volume = "53",

pages = "2860--2863",

journal = "Tetrahedron Letters",

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T1 - Cs 2CO 3 in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions

AU - Sahnoun, Sophian

AU - Messaoudi, Samir

AU - Peyrat, Jean François

AU - Brion, Jean Daniel

AU - Alami, Mouad

PY - 2012/6/6

Y1 - 2012/6/6

N2 - An efficient hydration reaction of various (hetero)aryl nitriles using Cs 2CO 3 in pyrrolidinone is described. This new metal-free protocol proved to be highly effective and general to synthesize a variety of (hetero)aryl amides.

AB - An efficient hydration reaction of various (hetero)aryl nitriles using Cs 2CO 3 in pyrrolidinone is described. This new metal-free protocol proved to be highly effective and general to synthesize a variety of (hetero)aryl amides.

KW - Amides

KW - Hydration

KW - Metal-free procedure

KW - Nitriles

U2 - 10.1016/j.tetlet.2012.03.117

DO - 10.1016/j.tetlet.2012.03.117

M3 - Article

AN - SCOPUS:84860834798

SN - 0040-4039

VL - 53

SP - 2860

EP - 2863

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 23

ER -

Cs 2CO 3 in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions

Résumé

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Contient cette citation

Cs ₂CO ₃ in pyrrolidinone promoted hydration of functionalized (hetero)aryl nitriles under metal-free conditions