Functional primary amines and diamines from α-aminoacids. A concise route to substituted 2-aminotetralins

Image Persented S-Phthalimidomethyl xanthates derived from various r-amino acids add efficiently to a range of unactivated alkenes to give a variety of highly functionalized, protected amines. In the case of phenylalanine and tyrosine derived xanthates, the adducts can be further converted into the rare 4-substituted 2-aminotetralines by a radical ring closure onto the aromatic ring.