Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites

Stéphan Vagner; Bruno Galy; Stéphane Pyronnet

doi:10.1093/embo-reports/kve208

Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites

Stéphan Vagner
, Bruno Galy
, Stéphane Pyronnet

Résultats de recherche: Contribution à un journal › Article de révision › Revue par des pairs

Résumé

Studies on the control of eukaryotic translation initiation by a cap-independent recruitment of the 40S ribosomal subunit to internal messenger RNA sequences called internal ribosome entry sites (IRESs) have shown that these sequence elements are present in a growing list of viral and cellular RNAs. Here we discuss their prevalence, mechanisms whereby they may function and their uses in regulating gene expression.

langue originale	Anglais
Pages (de - à)	893-898
Nombre de pages	6
journal	EMBO Reports
Volume	2
Numéro de publication	10
Les DOIs	https://doi.org/10.1093/embo-reports/kve208
état	Publié - 1 janv. 2001
Modification externe	Oui

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10.1093/embo-reports/kve208

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title = "Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites",

abstract = "Studies on the control of eukaryotic translation initiation by a cap-independent recruitment of the 40S ribosomal subunit to internal messenger RNA sequences called internal ribosome entry sites (IRESs) have shown that these sequence elements are present in a growing list of viral and cellular RNAs. Here we discuss their prevalence, mechanisms whereby they may function and their uses in regulating gene expression.",

author = "St{\'e}phan Vagner and Bruno Galy and St{\'e}phane Pyronnet",

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AU - Galy, Bruno

AU - Pyronnet, Stéphane

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N2 - Studies on the control of eukaryotic translation initiation by a cap-independent recruitment of the 40S ribosomal subunit to internal messenger RNA sequences called internal ribosome entry sites (IRESs) have shown that these sequence elements are present in a growing list of viral and cellular RNAs. Here we discuss their prevalence, mechanisms whereby they may function and their uses in regulating gene expression.

AB - Studies on the control of eukaryotic translation initiation by a cap-independent recruitment of the 40S ribosomal subunit to internal messenger RNA sequences called internal ribosome entry sites (IRESs) have shown that these sequence elements are present in a growing list of viral and cellular RNAs. Here we discuss their prevalence, mechanisms whereby they may function and their uses in regulating gene expression.

UR - https://www.scopus.com/pages/publications/0034764497

U2 - 10.1093/embo-reports/kve208

DO - 10.1093/embo-reports/kve208

M3 - Review article

C2 - 11600453

AN - SCOPUS:0034764497

SN - 1469-221X

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SP - 893

EP - 898

JO - EMBO Reports

JF - EMBO Reports

IS - 10

ER -

Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites

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