MatVPC: A user-friendly MATLAB-based tool for the simulation and evaluation of systems pharmacology models

K. Biliouris; M. Lavielle; M. N. Trame

doi:10.1002/psp4.12011

MatVPC: A user-friendly MATLAB-based tool for the simulation and evaluation of systems pharmacology models

K. Biliouris
, M. Lavielle
, M. N. Trame

University of Florida
INRIA

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

Quantitative systems pharmacology (QSP) models are progressively entering the arena of contemporary pharmacology. The efficient implementation and evaluation of complex QSP models necessitates the development of flexible computational tools that are built into QSP mainstream software. To this end, we present MatVPC, a versatile MATLAB-based tool that accommodates QSP models of any complexity level. MatVPC executes Monte Carlo simulations as well as automatic construction of visual predictive checks (VPCs) and quantified VPCs (QVPCs).

langue originale	Anglais
Pages (de - à)	547-557
Nombre de pages	11
journal	CPT: Pharmacometrics and Systems Pharmacology
Volume	4
Numéro de publication	9
Les DOIs	https://doi.org/10.1002/psp4.12011
état	Publié - 1 sept. 2015
Modification externe	Oui

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abstract = "Quantitative systems pharmacology (QSP) models are progressively entering the arena of contemporary pharmacology. The efficient implementation and evaluation of complex QSP models necessitates the development of flexible computational tools that are built into QSP mainstream software. To this end, we present MatVPC, a versatile MATLAB-based tool that accommodates QSP models of any complexity level. MatVPC executes Monte Carlo simulations as well as automatic construction of visual predictive checks (VPCs) and quantified VPCs (QVPCs).",

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AB - Quantitative systems pharmacology (QSP) models are progressively entering the arena of contemporary pharmacology. The efficient implementation and evaluation of complex QSP models necessitates the development of flexible computational tools that are built into QSP mainstream software. To this end, we present MatVPC, a versatile MATLAB-based tool that accommodates QSP models of any complexity level. MatVPC executes Monte Carlo simulations as well as automatic construction of visual predictive checks (VPCs) and quantified VPCs (QVPCs).

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DO - 10.1002/psp4.12011

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MatVPC: A user-friendly MATLAB-based tool for the simulation and evaluation of systems pharmacology models

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