Palladium-Mediated Labeling of Nucleic Acids

Eric Defrancq; Samir Messaoudi

doi:10.1002/cbic.201600599

Palladium-Mediated Labeling of Nucleic Acids

Eric Defrancq
, Samir Messaoudi

LTHE (UMR 5564 CNRS/IRD/Université de Grenoble)
Université Paris-Saclay

Résultats de recherche: Contribution à un journal › Article de révision › Revue par des pairs

Résumé

New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.

langue originale	Anglais
Pages (de - à)	426-431
Nombre de pages	6
journal	ChemBioChem
Volume	18
Numéro de publication	5
Les DOIs	https://doi.org/10.1002/cbic.201600599
état	Publié - 2 mars 2017
Modification externe	Oui

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10.1002/cbic.201600599

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title = "Palladium-Mediated Labeling of Nucleic Acids",

abstract = "New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.",

keywords = "Suzuki–Miyaura, cross-coupling, nucleic acids, oligonucleotides, palladium",

author = "Eric Defrancq and Samir Messaoudi",

note = "Publisher Copyright: {\textcopyright} 2017 Wiley-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2017",

month = mar,

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doi = "10.1002/cbic.201600599",

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T1 - Palladium-Mediated Labeling of Nucleic Acids

AU - Defrancq, Eric

AU - Messaoudi, Samir

PY - 2017/3/2

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N2 - New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.

AB - New applications of Pd-catalyzed coupling reactions (Suzuki–Miyaura, Sonogashira, and Stille–Migita coupling) for post-conjugation of nucleic acids have been developed recently. Breakthroughs in this area might now pave the way for the development of sophisticated DNA probes, which might be of great interest in chemical biology, nanotechnology, and bioanalysis, as well as in diagnostic domains.

KW - Suzuki–Miyaura

KW - cross-coupling

KW - nucleic acids

KW - oligonucleotides

KW - palladium

U2 - 10.1002/cbic.201600599

DO - 10.1002/cbic.201600599

M3 - Review article

C2 - 28000981

AN - SCOPUS:85013046141

SN - 1439-4227

VL - 18

SP - 426

EP - 431

JO - ChemBioChem

JF - ChemBioChem

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Palladium-Mediated Labeling of Nucleic Acids

Résumé

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