@inproceedings{0f92136ec8cb4ae586ed4e27f958586a,
title = "Patient-Specific biomechanical modeling of cardiac amyloidosis – A case study",
abstract = "We present a patient-specific biomechanical modeling framework and an initial case study for investigating cardiac amyloidosis (CA). Our patient-specific heartbeat simulations are in good agreement with the data, and our model calibration indicates that the major effect of CA in the biophysical behavior lies in a dramatic increase of the passive stiffness. We also conducted a preliminary trial for predicting the effects of pharmacological treatments – which is an important clinical challenge – based on the model combined with a simple venous return representation. This requires further investigation and validation, albeit provides some valuable preliminary insight.",
keywords = "Amyloidosis, Cardiac modelling, Heart failure, Patient-specific",
author = "D. Chapelle and A. Felder and R. Chabiniok and A. Guellich and Deux, \{J. F.\} and T. Damy",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015.; 8th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2015 ; Conference date: 25-06-2015 Through 27-06-2015",
year = "2015",
month = jan,
day = "1",
doi = "10.1007/978-3-319-20309-6\_34",
language = "English",
isbn = "9783319203089",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "295--303",
editor = "\{van Assen\}, Hans and Peter Bovendeerd and \{van Assen\}, Hans and Peter Bovendeerd and Tammo Delhaas and Tammo Delhaas",
booktitle = "Functional Imaging and Modeling of the Heart - 8th International Conference, FIMH 2015, Proceedings",
}