Picosecond ultrasounds as elasticity probes in neuron-like cells models

Alexis Viel; Emmanuel Péronne; Océane Sénépart; Loïc Becerra; Claire Legay; Fannie Semprez; Léa Trichet; Thibaud Coradin; Ahmed Hamraoui; Laurent Belliard

doi:10.1063/1.5129783

Picosecond ultrasounds as elasticity probes in neuron-like cells models

Alexis Viel
, Emmanuel Péronne
, Océane Sénépart
, Loïc Becerra
, Claire Legay
, Fannie Semprez
, Léa Trichet
, Thibaud Coradin
, Ahmed Hamraoui
, Laurent Belliard

Sorbonne Université
Université de Paris
Laboratoire Licorne
Laboratoire de Probabilités et Modèles Aléatoires

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

18 Citations (Scopus)

Résumé

We report on elasticity measurements in neuronlike cells using picosecond acoustics pump and probe spectroscopy. The stimulated Brillouin oscillations were mapped in PC12 cells to reveal their internal elastic structure. Thanks to a Pearson correlation coefficient mapping, different areas could be distinguished. The nucleus material shows a bulk modulus equal to 12.9 GPa in the case of a dry cell. Attenuation of the Brillouin signature gives access to dynamical longitudinal viscosity equal to 10.6 mPa âs, one order of magnitude higher than that of water. The modulus considerably drops to 2.6 GPa in the most physiologically relevant case of a hydrated cell.

langue originale	Anglais
Numéro d'article	213701
journal	Applied Physics Letters
Volume	115
Numéro de publication	21
Les DOIs	https://doi.org/10.1063/1.5129783
état	Publié - 18 nov. 2019

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10.1063/1.5129783

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abstract = "We report on elasticity measurements in neuronlike cells using picosecond acoustics pump and probe spectroscopy. The stimulated Brillouin oscillations were mapped in PC12 cells to reveal their internal elastic structure. Thanks to a Pearson correlation coefficient mapping, different areas could be distinguished. The nucleus material shows a bulk modulus equal to 12.9 GPa in the case of a dry cell. Attenuation of the Brillouin signature gives access to dynamical longitudinal viscosity equal to 10.6 mPa {\^a}s, one order of magnitude higher than that of water. The modulus considerably drops to 2.6 GPa in the most physiologically relevant case of a hydrated cell.",

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AU - Viel, Alexis

AU - Péronne, Emmanuel

AU - Sénépart, Océane

AU - Becerra, Loïc

AU - Legay, Claire

AU - Semprez, Fannie

AU - Trichet, Léa

AU - Coradin, Thibaud

AU - Hamraoui, Ahmed

AU - Belliard, Laurent

PY - 2019/11/18

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N2 - We report on elasticity measurements in neuronlike cells using picosecond acoustics pump and probe spectroscopy. The stimulated Brillouin oscillations were mapped in PC12 cells to reveal their internal elastic structure. Thanks to a Pearson correlation coefficient mapping, different areas could be distinguished. The nucleus material shows a bulk modulus equal to 12.9 GPa in the case of a dry cell. Attenuation of the Brillouin signature gives access to dynamical longitudinal viscosity equal to 10.6 mPa âs, one order of magnitude higher than that of water. The modulus considerably drops to 2.6 GPa in the most physiologically relevant case of a hydrated cell.

AB - We report on elasticity measurements in neuronlike cells using picosecond acoustics pump and probe spectroscopy. The stimulated Brillouin oscillations were mapped in PC12 cells to reveal their internal elastic structure. Thanks to a Pearson correlation coefficient mapping, different areas could be distinguished. The nucleus material shows a bulk modulus equal to 12.9 GPa in the case of a dry cell. Attenuation of the Brillouin signature gives access to dynamical longitudinal viscosity equal to 10.6 mPa âs, one order of magnitude higher than that of water. The modulus considerably drops to 2.6 GPa in the most physiologically relevant case of a hydrated cell.

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DO - 10.1063/1.5129783

M3 - Article

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SN - 0003-6951

VL - 115

JO - Applied Physics Letters

JF - Applied Physics Letters

IS - 21

M1 - 213701

ER -

Picosecond ultrasounds as elasticity probes in neuron-like cells models

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