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Post-transcriptional control of gene expression through subcellular relocalization of mRNA binding proteins

  • INSERM U869
  • Institut Claudius Regaud
  • Université Paul Sabatier
  • University of Ottawa
  • Atlantic Cancer Research Institute

Résultats de recherche: Contribution à un journalArticleRevue par des pairs

Résumé

Eukaryotic cells have developed multiple mechanisms to respond to different physiological cues, such as cellular stress, which allow the cells to adapt themselves to their new environment. The regulation of post-transcriptional gene expression is an important component of the cellular stress response and is mediated by mRNA binding proteins (mRBPs). Recently, several studies have shown that regulated subcellular localization of mRBPs upon diverse stimuli (such as cellular stress) provides an additional level of regulation for gene expression.

langue originaleAnglais
Pages (de - à)1395-1403
Nombre de pages9
journalBiochemical Pharmacology
Volume76
Numéro de publication11
Les DOIs
étatPublié - 1 déc. 2008
Modification externeOui

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