Sandmeyer trifluoromethylation of arenediazonium tetrafluoroborates

Grégory Danoun; Bilguun Bayarmagnai; Matthias F. Grünberg; Lukas J. Gooßen

doi:10.1002/anie.201304276

Sandmeyer trifluoromethylation of arenediazonium tetrafluoroborates

Grégory Danoun
, Bilguun Bayarmagnai
, Matthias F. Grünberg
, Lukas J. Gooßen

University of Kaiserslautern

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

183 Citations (Scopus)

Résumé

Copper capabilities: Diazonium salts are converted into the corresponding trifluoromethyl derivatives in the presence of a trifluoromethyl-copper complex generated in situ from CuSCN and the inexpensive, easy-to-use trifluoromethylating reagent Me₃Si-CF₃ (see scheme). This Sandmeyer-type reaction allows the straightforward synthesis of trifluoromethylated arenes and heteroarenes from the corresponding amines.

langue originale	Anglais
Pages (de - à)	7972-7975
Nombre de pages	4
journal	Angewandte Chemie - International Edition
Volume	52
Numéro de publication	31
Les DOIs	https://doi.org/10.1002/anie.201304276
état	Publié - 29 juil. 2013
Modification externe	Oui

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10.1002/anie.201304276

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abstract = "Copper capabilities: Diazonium salts are converted into the corresponding trifluoromethyl derivatives in the presence of a trifluoromethyl-copper complex generated in situ from CuSCN and the inexpensive, easy-to-use trifluoromethylating reagent Me3Si-CF3 (see scheme). This Sandmeyer-type reaction allows the straightforward synthesis of trifluoromethylated arenes and heteroarenes from the corresponding amines.",

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author = "Gr{\'e}gory Danoun and Bilguun Bayarmagnai and Gr{\"u}nberg, \{Matthias F.\} and Goo{\ss}en, \{Lukas J.\}",

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AU - Danoun, Grégory

AU - Bayarmagnai, Bilguun

AU - Grünberg, Matthias F.

AU - Gooßen, Lukas J.

PY - 2013/7/29

Y1 - 2013/7/29

N2 - Copper capabilities: Diazonium salts are converted into the corresponding trifluoromethyl derivatives in the presence of a trifluoromethyl-copper complex generated in situ from CuSCN and the inexpensive, easy-to-use trifluoromethylating reagent Me3Si-CF3 (see scheme). This Sandmeyer-type reaction allows the straightforward synthesis of trifluoromethylated arenes and heteroarenes from the corresponding amines.

AB - Copper capabilities: Diazonium salts are converted into the corresponding trifluoromethyl derivatives in the presence of a trifluoromethyl-copper complex generated in situ from CuSCN and the inexpensive, easy-to-use trifluoromethylating reagent Me3Si-CF3 (see scheme). This Sandmeyer-type reaction allows the straightforward synthesis of trifluoromethylated arenes and heteroarenes from the corresponding amines.

KW - Sandmeyer reaction

KW - copper

KW - diazonium salts

KW - trifluoromethylation

U2 - 10.1002/anie.201304276

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Sandmeyer trifluoromethylation of arenediazonium tetrafluoroborates

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