SECISDesign: A server to design SECIS-elements within the coding sequence

Anke Busch; Sebastian Will; Rolf Backofen

doi:10.1093/bioinformatics/bti507

SECISDesign: A server to design SECIS-elements within the coding sequence

Anke Busch
, Sebastian Will
, Rolf Backofen

Friedrich-Schiller University

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

6 Citations (Scopus)

Résumé

Summary: SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli.

langue originale	Anglais
Pages (de - à)	3312-3313
Nombre de pages	2
journal	Bioinformatics
Volume	21
Numéro de publication	15
Les DOIs	https://doi.org/10.1093/bioinformatics/bti507
état	Publié - 1 août 2005
Modification externe	Oui

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10.1093/bioinformatics/bti507

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title = "SECISDesign: A server to design SECIS-elements within the coding sequence",

abstract = "Summary: SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli.",

author = "Anke Busch and Sebastian Will and Rolf Backofen",

year = "2005",

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AU - Busch, Anke

AU - Will, Sebastian

AU - Backofen, Rolf

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N2 - Summary: SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli.

AB - Summary: SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli.

UR - https://www.scopus.com/pages/publications/25144466655

U2 - 10.1093/bioinformatics/bti507

DO - 10.1093/bioinformatics/bti507

M3 - Article

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JO - Bioinformatics

JF - Bioinformatics

IS - 15

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SECISDesign: A server to design SECIS-elements within the coding sequence

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