Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

Ludovic Mayer; Abdallah Slablab; Géraldine Dantelle; Vincent Jacques; Aude Marie Lepagnol-Bestel; Sandrine Perruchas; Piernicola Spinicelli; Alice Thomas; Dominique Chauvat; Michel Simonneau; Thierry Gacoin; Jean François Roch

doi:10.1039/c3nr01251d

Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

Ludovic Mayer
, Abdallah Slablab
, Géraldine Dantelle
, Vincent Jacques
, Aude Marie Lepagnol-Bestel
, Sandrine Perruchas
, Piernicola Spinicelli
, Alice Thomas
, Dominique Chauvat
, Michel Simonneau
, Thierry Gacoin
, Jean François Roch

ENS Paris-Saclay
Laboratoire Aimé Cotton
CEA-IG
Université de Paris

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

We report an efficient colloidal synthesis of KTiOPO₄ (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

langue originale	Anglais
Pages (de - à)	8466-8471
Nombre de pages	6
journal	Nanoscale
Volume	5
Numéro de publication	18
Les DOIs	https://doi.org/10.1039/c3nr01251d
état	Publié - 21 sept. 2013

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10.1039/c3nr01251d

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title = "Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons",

abstract = "We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.",

author = "Ludovic Mayer and Abdallah Slablab and G{\'e}raldine Dantelle and Vincent Jacques and Lepagnol-Bestel, \{Aude Marie\} and Sandrine Perruchas and Piernicola Spinicelli and Alice Thomas and Dominique Chauvat and Michel Simonneau and Thierry Gacoin and Roch, \{Jean Fran{\c c}ois\}",

year = "2013",

month = sep,

day = "21",

doi = "10.1039/c3nr01251d",

language = "English",

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journal = "Nanoscale",

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T1 - Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

AU - Mayer, Ludovic

AU - Slablab, Abdallah

AU - Dantelle, Géraldine

AU - Jacques, Vincent

AU - Lepagnol-Bestel, Aude Marie

AU - Perruchas, Sandrine

AU - Spinicelli, Piernicola

AU - Thomas, Alice

AU - Chauvat, Dominique

AU - Simonneau, Michel

AU - Gacoin, Thierry

AU - Roch, Jean François

PY - 2013/9/21

Y1 - 2013/9/21

N2 - We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

AB - We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

U2 - 10.1039/c3nr01251d

DO - 10.1039/c3nr01251d

M3 - Article

C2 - 23852161

AN - SCOPUS:84883180939

SN - 2040-3364

VL - 5

SP - 8466

EP - 8471

JO - Nanoscale

JF - Nanoscale

IS - 18

ER -

Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

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