Synthesis of 2,3-Substituted β- N-Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis

Guangkuan Zhao; Mingxiang Zhu; Olivier Provot; Mouad Alami; Samir Messaoudi

doi:10.1021/acs.orglett.9b03893

Synthesis of 2,3-Substituted β- N-Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis

Guangkuan Zhao
, Mingxiang Zhu
, Olivier Provot
, Mouad Alami
, Samir Messaoudi

Université Paris-Sud

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

15 Citations (Scopus)

Résumé

An efficient and selective C-H activation method of readily available β-N-aryl glycosides with various alkynes has been established. Using [Cp*RhCl₂]₂ as a catalyst and AgSbF₆ in DCE, this protocol proved to be general to prepare a variety of 2,3-substituted N-glycosyl indoles in good yields.

langue originale	Anglais
Pages (de - à)	57-61
Nombre de pages	5
journal	Organic Letters
Volume	22
Numéro de publication	1
Les DOIs	https://doi.org/10.1021/acs.orglett.9b03893
état	Publié - 3 janv. 2020
Modification externe	Oui

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10.1021/acs.orglett.9b03893

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title = "Synthesis of 2,3-Substituted β- N-Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis",

abstract = "An efficient and selective C-H activation method of readily available β-N-aryl glycosides with various alkynes has been established. Using [Cp*RhCl2]2 as a catalyst and AgSbF6 in DCE, this protocol proved to be general to prepare a variety of 2,3-substituted N-glycosyl indoles in good yields.",

author = "Guangkuan Zhao and Mingxiang Zhu and Olivier Provot and Mouad Alami and Samir Messaoudi",

note = "Publisher Copyright: {\textcopyright} 2019 American Chemical Society.",

year = "2020",

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day = "3",

doi = "10.1021/acs.orglett.9b03893",

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volume = "22",

pages = "57--61",

journal = "Organic Letters",

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T1 - Synthesis of 2,3-Substituted β- N-Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis

AU - Zhao, Guangkuan

AU - Zhu, Mingxiang

AU - Provot, Olivier

AU - Alami, Mouad

AU - Messaoudi, Samir

PY - 2020/1/3

Y1 - 2020/1/3

N2 - An efficient and selective C-H activation method of readily available β-N-aryl glycosides with various alkynes has been established. Using [Cp*RhCl2]2 as a catalyst and AgSbF6 in DCE, this protocol proved to be general to prepare a variety of 2,3-substituted N-glycosyl indoles in good yields.

AB - An efficient and selective C-H activation method of readily available β-N-aryl glycosides with various alkynes has been established. Using [Cp*RhCl2]2 as a catalyst and AgSbF6 in DCE, this protocol proved to be general to prepare a variety of 2,3-substituted N-glycosyl indoles in good yields.

U2 - 10.1021/acs.orglett.9b03893

DO - 10.1021/acs.orglett.9b03893

M3 - Article

C2 - 31860311

AN - SCOPUS:85077197469

SN - 1523-7060

VL - 22

SP - 57

EP - 61

JO - Organic Letters

JF - Organic Letters

IS - 1

ER -

Synthesis of 2,3-Substituted β- N-Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis

Résumé

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