Résumé
In this article we present the Biochemical Abstract Machine BIOCHAM and advocate its use as a formal modeling environment for networks biology. Biocham provides a precise semantics to biomolecular interaction maps. Based on this formal semantics, the Biocham system offers automated reasoning tools for querying the temporal properties of the system under all its possible behaviors. We present the main features of Biocham, provide details on a simple example of the MAPK signaling cascade and prove some results on the equivalence of models w.r.t. their temporal properties.
| langue originale | Anglais |
|---|---|
| Pages (de - à) | 172-191 |
| Nombre de pages | 20 |
| journal | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
| Volume | 3082 |
| Les DOIs | |
| état | Publié - 1 janv. 2005 |
| Modification externe | Oui |
| Evénement | International Conference on Computational Methods in Systems Biology, CMSB 2004 - Paris, France Durée: 26 mai 2004 → 28 mai 2004 |
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