TiCl 4 -Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions

Sudipta Ponra; Aude Nyadanu; Sylvie Maurin; Laurent El Kaïm; Laurence Grimaud; Maxime R. Vitale

doi:10.1055/s-0036-1591733

TiCl ₄ -Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions

Sudipta Ponra
, Aude Nyadanu
, Sylvie Maurin
, Laurent El Kaïm
, Laurence Grimaud
, Maxime R. Vitale

Laboratoire Charles Friedel (LCF)
PSL research University & IPSL
Université Paris-Saclay

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

9 Citations (Scopus)

Résumé

The isocyanide insertion into sulfanyl-phthalides under Lewis acid conditions is reported with full details. This sequential three-component reaction affords a new straightforward and highly convenient method for the preparation of 3-amino-4-sulfanyl isocoumarins, the potential of which is still unexplored.

langue originale	Anglais
Pages (de - à)	1331-1342
Nombre de pages	12
journal	Synthesis
Volume	50
Numéro de publication	6
Les DOIs	https://doi.org/10.1055/s-0036-1591733
état	Publié - 15 mars 2018
Modification externe	Oui

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10.1055/s-0036-1591733

Contient cette citation

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title = "TiCl 4 -Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions",

abstract = "The isocyanide insertion into sulfanyl-phthalides under Lewis acid conditions is reported with full details. This sequential three-component reaction affords a new straightforward and highly convenient method for the preparation of 3-amino-4-sulfanyl isocoumarins, the potential of which is still unexplored.",

keywords = "isocoumarins, isocyanides, thio-Passerini reaction, thiocarbonyl surrogates",

author = "Sudipta Ponra and Aude Nyadanu and Sylvie Maurin and \{El Ka{\"i}m\}, Laurent and Laurence Grimaud and Vitale, \{Maxime R.\}",

year = "2018",

month = mar,

day = "15",

doi = "10.1055/s-0036-1591733",

language = "English",

volume = "50",

pages = "1331--1342",

journal = "Synthesis",

issn = "0039-7881",

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TY - JOUR

T1 - TiCl 4 -Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions

AU - Ponra, Sudipta

AU - Nyadanu, Aude

AU - Maurin, Sylvie

AU - El Kaïm, Laurent

AU - Grimaud, Laurence

AU - Vitale, Maxime R.

PY - 2018/3/15

Y1 - 2018/3/15

N2 - The isocyanide insertion into sulfanyl-phthalides under Lewis acid conditions is reported with full details. This sequential three-component reaction affords a new straightforward and highly convenient method for the preparation of 3-amino-4-sulfanyl isocoumarins, the potential of which is still unexplored.

AB - The isocyanide insertion into sulfanyl-phthalides under Lewis acid conditions is reported with full details. This sequential three-component reaction affords a new straightforward and highly convenient method for the preparation of 3-amino-4-sulfanyl isocoumarins, the potential of which is still unexplored.

KW - isocoumarins

KW - isocyanides

KW - thio-Passerini reaction

KW - thiocarbonyl surrogates

U2 - 10.1055/s-0036-1591733

DO - 10.1055/s-0036-1591733

M3 - Article

AN - SCOPUS:85038371806

SN - 0039-7881

VL - 50

SP - 1331

EP - 1342

JO - Synthesis

JF - Synthesis

IS - 6

ER -

TiCl 4 -Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions

Résumé

Accès au document

Empreinte digitale

Contient cette citation

TiCl ₄ -Mediated Synthesis of 3,4-Hetero-Disubstituted Isocoumarins by Means of Isocyanide Insertion Reactions