Time-resolved circular dichroism in carbonmonoxy-myoglobin: The central role of the proximal histidine

Thibault Dartigalongue; François Hache

doi:10.1002/chir.20254

Time-resolved circular dichroism in carbonmonoxy-myoglobin: The central role of the proximal histidine

Thibault Dartigalongue
, François Hache

Institut Polytechnique de Paris

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

A calculation of the circular dichroism (CD) spectra of carbonmonoxy-and deoxy-myoglobin is carried out in relation to a time-resolved CD experiment. This calculation allows us to assign a dominant role to the proximal histidine in the definition of the electronic normal modes and to interpret the transient CD structure observed in a strain of the proximal histidine. This strain builds up in 10 ps and relaxes in 50 ps as the protein evolves towards its deoxy form.

langue originale	Anglais
Pages (de - à)	273-278
Nombre de pages	6
journal	Chirality
Volume	18
Numéro de publication	4
Les DOIs	https://doi.org/10.1002/chir.20254
état	Publié - 9 mai 2006

Accès au document

10.1002/chir.20254

Autres fichiers et liens

Lien vers la publication dans Scopus

Contient cette citation

@article{a70112e5915a41abb65ec1d6999a5506,

title = "Time-resolved circular dichroism in carbonmonoxy-myoglobin: The central role of the proximal histidine",

abstract = "A calculation of the circular dichroism (CD) spectra of carbonmonoxy-and deoxy-myoglobin is carried out in relation to a time-resolved CD experiment. This calculation allows us to assign a dominant role to the proximal histidine in the definition of the electronic normal modes and to interpret the transient CD structure observed in a strain of the proximal histidine. This strain builds up in 10 ps and relaxes in 50 ps as the protein evolves towards its deoxy form.",

keywords = "Myoglobin, Time-resolved circular dichroism",

author = "Thibault Dartigalongue and Fran{\c c}ois Hache",

year = "2006",

month = may,

day = "9",

doi = "10.1002/chir.20254",

language = "English",

volume = "18",

pages = "273--278",

journal = "Chirality",

issn = "0899-0042",

number = "4",

}

TY - JOUR

T1 - Time-resolved circular dichroism in carbonmonoxy-myoglobin

T2 - The central role of the proximal histidine

AU - Dartigalongue, Thibault

AU - Hache, François

PY - 2006/5/9

Y1 - 2006/5/9

N2 - A calculation of the circular dichroism (CD) spectra of carbonmonoxy-and deoxy-myoglobin is carried out in relation to a time-resolved CD experiment. This calculation allows us to assign a dominant role to the proximal histidine in the definition of the electronic normal modes and to interpret the transient CD structure observed in a strain of the proximal histidine. This strain builds up in 10 ps and relaxes in 50 ps as the protein evolves towards its deoxy form.

AB - A calculation of the circular dichroism (CD) spectra of carbonmonoxy-and deoxy-myoglobin is carried out in relation to a time-resolved CD experiment. This calculation allows us to assign a dominant role to the proximal histidine in the definition of the electronic normal modes and to interpret the transient CD structure observed in a strain of the proximal histidine. This strain builds up in 10 ps and relaxes in 50 ps as the protein evolves towards its deoxy form.

KW - Myoglobin

KW - Time-resolved circular dichroism

UR - https://www.scopus.com/pages/publications/33646246146

U2 - 10.1002/chir.20254

DO - 10.1002/chir.20254

M3 - Article

C2 - 16534800

AN - SCOPUS:33646246146

SN - 0899-0042

VL - 18

SP - 273

EP - 278

JO - Chirality

JF - Chirality

IS - 4

ER -

Time-resolved circular dichroism in carbonmonoxy-myoglobin: The central role of the proximal histidine

Résumé

Accès au document

Autres fichiers et liens

Empreinte digitale

Contient cette citation