Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands

Jun Zhou; Anne Bourdoncle; Frédéric Rosu; Valérie Gabelica; Jean Louis Mergny

doi:10.1002/anie.201205390

Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands

Jun Zhou
, Anne Bourdoncle
, Frédéric Rosu
, Valérie Gabelica
, Jean Louis Mergny

Univ. Bordeaux
INSERM, U869, IECB
University of Liège
Univ. Poitiers

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li⁺ ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na⁺ ions and characterized by gel electrophoresis and spectroscopy.

langue originale	Anglais
Pages (de - à)	11002-11005
Nombre de pages	4
journal	Angewandte Chemie - International Edition
Volume	51
Numéro de publication	44
Les DOIs	https://doi.org/10.1002/anie.201205390
état	Publié - 29 oct. 2012
Modification externe	Oui

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10.1002/anie.201205390

Contient cette citation

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title = "Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands",

abstract = "In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li+ ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na+ ions and characterized by gel electrophoresis and spectroscopy.",

keywords = "DNA, G-quadruplexes, circular dichroism, electrospray mass spectrometry, nucleic acids",

author = "Jun Zhou and Anne Bourdoncle and Fr{\'e}d{\'e}ric Rosu and Val{\'e}rie Gabelica and Mergny, \{Jean Louis\}",

year = "2012",

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day = "29",

doi = "10.1002/anie.201205390",

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journal = "Angewandte Chemie - International Edition",

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AU - Bourdoncle, Anne

AU - Rosu, Frédéric

AU - Gabelica, Valérie

AU - Mergny, Jean Louis

PY - 2012/10/29

Y1 - 2012/10/29

N2 - In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li+ ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na+ ions and characterized by gel electrophoresis and spectroscopy.

AB - In my (DNA) dreams: A tri-G-quadruplex was constructed from three strands (T1-T3) of DNA using duplex formation to guide the G-rich tracts into close proximity with the addition of Li+ ions (see scheme). The defined G-quadruplex structure was formed upon addition of Na+ ions and characterized by gel electrophoresis and spectroscopy.

KW - DNA

KW - G-quadruplexes

KW - circular dichroism

KW - electrospray mass spectrometry

KW - nucleic acids

U2 - 10.1002/anie.201205390

DO - 10.1002/anie.201205390

M3 - Article

C2 - 23038222

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SN - 1433-7851

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JF - Angewandte Chemie - International Edition

IS - 44

ER -

Tri-G-quadruplex: Controlled assembly of a G-quadruplex structure from three G-rich strands

Résumé

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