Ugi-Smiles Couplings of Purine Derivatives

Abdelbari Ben Abdessalem; Raoudha Abderrahim; Aurélie Dos Santos; Laurent El Kaïm; Laurence Grimaud

doi:10.1055/s-0036-1588117

Ugi-Smiles Couplings of Purine Derivatives

Abdelbari Ben Abdessalem
, Raoudha Abderrahim
, Aurélie Dos Santos
, Laurent El Kaïm
, Laurence Grimaud

Université Paris-Saclay
Université de Carthage
PSL Research University
PSL research University & IPSL

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

Résumé

Purines may be involved in Ugi-Smiles coupling as shown by the successful formation of thiocarboxamide derivatives from 6-mercaptopurine. This multicomponent coupling affords a very straightforward access to functionalized adenine derivatives, which are widely represented among natural products of medicinal interest.

langue originale	Anglais
Numéro d'article	st-2016-b0581-l
Pages (de - à)	691-694
Nombre de pages	4
journal	Synlett
Volume	28
Numéro de publication	6
Les DOIs	https://doi.org/10.1055/s-0036-1588117
état	Publié - 1 avr. 2017
Modification externe	Oui

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10.1055/s-0036-1588117

Contient cette citation

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title = "Ugi-Smiles Couplings of Purine Derivatives",

abstract = "Purines may be involved in Ugi-Smiles coupling as shown by the successful formation of thiocarboxamide derivatives from 6-mercaptopurine. This multicomponent coupling affords a very straightforward access to functionalized adenine derivatives, which are widely represented among natural products of medicinal interest.",

keywords = "Ugi-Smiles, adenines, isocyanide, multicomponent, purines, thioamides",

author = "Abdessalem, \{Abdelbari Ben\} and Raoudha Abderrahim and \{Dos Santos\}, Aur{\'e}lie and \{El Ka{\"i}m\}, Laurent and Laurence Grimaud",

note = "Publisher Copyright: {\textcopyright} Georg Thieme VerlagStuttgart · New York.",

year = "2017",

month = apr,

day = "1",

doi = "10.1055/s-0036-1588117",

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AU - Abdessalem, Abdelbari Ben

AU - Abderrahim, Raoudha

AU - Dos Santos, Aurélie

AU - El Kaïm, Laurent

AU - Grimaud, Laurence

N1 - Publisher Copyright: © Georg Thieme VerlagStuttgart · New York.

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Purines may be involved in Ugi-Smiles coupling as shown by the successful formation of thiocarboxamide derivatives from 6-mercaptopurine. This multicomponent coupling affords a very straightforward access to functionalized adenine derivatives, which are widely represented among natural products of medicinal interest.

AB - Purines may be involved in Ugi-Smiles coupling as shown by the successful formation of thiocarboxamide derivatives from 6-mercaptopurine. This multicomponent coupling affords a very straightforward access to functionalized adenine derivatives, which are widely represented among natural products of medicinal interest.

KW - Ugi-Smiles

KW - adenines

KW - isocyanide

KW - multicomponent

KW - purines

KW - thioamides

U2 - 10.1055/s-0036-1588117

DO - 10.1055/s-0036-1588117

M3 - Article

AN - SCOPUS:85001574774

SN - 0936-5214

VL - 28

SP - 691

EP - 694

JO - Synlett

JF - Synlett

IS - 6

M1 - st-2016-b0581-l

ER -

Ugi-Smiles Couplings of Purine Derivatives

Résumé

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