Zinc Chloride Mediated Synthesis of 3H-Oxazol-2-one and Pyrrolo-oxazin-1-one from Ynamide

Loïc Habert; Romain Sallio; Muriel Durandetti; Corinne Gosmini; Isabelle Gillaizeau

doi:10.1002/ejoc.201900428

Zinc Chloride Mediated Synthesis of 3H-Oxazol-2-one and Pyrrolo-oxazin-1-one from Ynamide

Loïc Habert
, Romain Sallio
, Muriel Durandetti
, Corinne Gosmini
, Isabelle Gillaizeau

conventionnée avec l'Université d'Orléans
Normandie Université
CNRS

Résultats de recherche: Contribution à un journal › Article › Revue par des pairs

25 Citations (Scopus)

Résumé

A simple zinc chloride mediated cyclization of ynamidyl N-carbamates or 2-ynamidyl-(hetero)arylcarboxylates is achieved under mild reaction conditions, leading to the synthesis of useful heterocyclic scaffolds, 3H-oxazol-2-ones and pyrrolo-oxazin-1-ones, with good yields.

langue originale	Anglais
Pages (de - à)	5175-5179
Nombre de pages	5
journal	European Journal of Organic Chemistry
Volume	2019
Numéro de publication	31-32
Les DOIs	https://doi.org/10.1002/ejoc.201900428
état	Publié - 1 sept. 2019
Modification externe	Oui

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10.1002/ejoc.201900428

Contient cette citation

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title = "Zinc Chloride Mediated Synthesis of 3H-Oxazol-2-one and Pyrrolo-oxazin-1-one from Ynamide",

abstract = "A simple zinc chloride mediated cyclization of ynamidyl N-carbamates or 2-ynamidyl-(hetero)arylcarboxylates is achieved under mild reaction conditions, leading to the synthesis of useful heterocyclic scaffolds, 3H-oxazol-2-ones and pyrrolo-oxazin-1-ones, with good yields.",

keywords = "Cyclization, Oxazolone, Pyrrolo-oxazinones, Ynamide, Zinc chloride",

author = "Lo{\"i}c Habert and Romain Sallio and Muriel Durandetti and Corinne Gosmini and Isabelle Gillaizeau",

note = "Publisher Copyright: {\textcopyright} 2019 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2019",

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doi = "10.1002/ejoc.201900428",

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T1 - Zinc Chloride Mediated Synthesis of 3H-Oxazol-2-one and Pyrrolo-oxazin-1-one from Ynamide

AU - Habert, Loïc

AU - Sallio, Romain

AU - Durandetti, Muriel

AU - Gosmini, Corinne

AU - Gillaizeau, Isabelle

PY - 2019/9/1

Y1 - 2019/9/1

N2 - A simple zinc chloride mediated cyclization of ynamidyl N-carbamates or 2-ynamidyl-(hetero)arylcarboxylates is achieved under mild reaction conditions, leading to the synthesis of useful heterocyclic scaffolds, 3H-oxazol-2-ones and pyrrolo-oxazin-1-ones, with good yields.

AB - A simple zinc chloride mediated cyclization of ynamidyl N-carbamates or 2-ynamidyl-(hetero)arylcarboxylates is achieved under mild reaction conditions, leading to the synthesis of useful heterocyclic scaffolds, 3H-oxazol-2-ones and pyrrolo-oxazin-1-ones, with good yields.

KW - Cyclization

KW - Oxazolone

KW - Pyrrolo-oxazinones

KW - Ynamide

KW - Zinc chloride

U2 - 10.1002/ejoc.201900428

DO - 10.1002/ejoc.201900428

M3 - Article

AN - SCOPUS:85071529712

SN - 1434-193X

VL - 2019

SP - 5175

EP - 5179

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 31-32

ER -

Zinc Chloride Mediated Synthesis of 3H-Oxazol-2-one and Pyrrolo-oxazin-1-one from Ynamide

Résumé

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